Aspire HFI Blog

Exploring Genetic Testing at Aspire HFI

Posted on February 15th, 2024

For aspiring parents trying to conceive, genetic testing can be an important consideration. Genetic testing, including preimplantation genetic testing (PGT), provides valuable insights into inheritable disorders and chromosomal abnormalities, supporting the best possible outcomes for every aspiring parent. Fertility specialists recommend and perform the most appropriate genetic tests for everyone’s unique needs, helping them understand their genetic risks and make informed decisions about their fertility treatment. Discover how genetic testing can help you on your path to a healthy pregnancy and a brighter future.

The Value of Genetic Testing

Depending on your unique needs, genetic testing is sometimes advised by fertility specialists based on factors like medical and family histories. It can provide valuable information about potential pregnancy risks without invasive testing.

During your initial consultation, you can be screened for recessive genetic diseases, like cystic fibrosis or sickle cell anemia. These diseases require two abnormal gene copies to develop, and individuals are often otherwise healthy without symptoms. Genetic testing can also screen for dominant conditions, which are more likely to affect multiple family members, such as recurrent breast or ovarian cancer (BRCA1 and BRCA2 mutations), or Huntington’s disease. Additionally, genetic testing may identify new mutations that are not shared by other family members.

Preimplantation Genetic Testing: A Comprehensive Overview

PGT is a valuable tool for aspiring parents considering in vitro fertilization (IVF) to build their families. PGT encompasses two main types: preimplantation genetic testing for monogenic disorders (PGT-M) and preimplantation genetic testing for aneuploidy (PGT-A).

During PGT, embryos created through IVF are biopsied to extract a few cells. These cells are then analyzed to determine their genetic makeup, identifying any abnormalities or genetic conditions. This information helps fertility specialists select embryos without these issues for transfer, increasing the chances of a successful pregnancy.

PGT-M, formerly known as preimplantation genetic diagnosis (PGD), is chosen by many IVF patients to identify specific genetic disorders in embryos, which is particularly crucial for individuals or couples with a known family history of inheritable genetic conditions.

PGT-A, formerly known as preimplantation genetic screening (PGS) evaluates an embryo’s chromosomes. Healthy embryos have 46 chromosomes, with 23 each from the egg and sperm. Any irregularity in the number of chromosomes (aneuploidy) can disrupt embryo growth, development, and function. PGT-A is used to identify embryos with aneuploidy disorders, such as Down syndrome, or to reduce the risk of miscarriage.

Explore the Benefits of Genetic Testing

Genetic testing can be a powerful tool in understanding and addressing potential challenges on your path to parenthood. At Aspire HFI, our team of specialists is dedicated to providing personalized care and the most advanced genetic testing options available, offering each aspiring parent invaluable insights to make informed decisions. Take the next step in your family-building journey by scheduling a consultation with Aspire Houston Fertility Institute today.

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